American Board of Surgery Qualifying Exam (ABS QE) Practice Test

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What characteristic defines a type 1 gastric carcinoid associated with chronic atrophic gastritis?

Size larger than 1 cm
Multiple lesions
Rapid growth
Frequent metastasis

The correct answer is: Multiple lesions

A type 1 gastric carcinoid associated with chronic atrophic gastritis is characterized by the presence of multiple lesions. This type of carcinoid tumor often arises in the setting of chronic atrophic gastritis, which is commonly associated with autoimmune conditions leading to the destruction of gastric mucosa and subsequent hypergastrinemia. The elevated gastrin levels promote the development of multiple neuroendocrine tumors rather than a single, larger tumor. In type 1 gastric carcinoids, the lesions are typically small and numerous, and they generally do not exhibit aggressive behavior. This contrasts with other tumor types, where characteristics such as size, growth rate, or tendency for metastasis are prominent. For instance, while some carcinoids can grow rapidly or have higher metastatic potential, type 1 tumors are generally indolent and have a very low risk of metastasis. This further emphasizes the significance of recognizing the multiplicity of tumors in this specific context of gastric carcinoids linked with chronic atrophic gastritis.