American Board of Surgery Qualifying Exam (ABS QE) Practice Test

Which type of melanoma is characterized as the least aggressive?

1. Nodular melanoma

2. Superficial spreading melanoma

3. Lentigo melanoma

4. Desmoplastic melanoma

The correct answer is: Lentigo melanoma

Lentigo melanoma is considered the least aggressive type of melanoma due to its distinct histological presentation and typically slow growth pattern. This type of melanoma is often found in older adults, primarily on sun-damaged skin, and is characterized by a prolonged radial growth phase before it potentially progresses to the vertical growth phase, which is more aggressive. The characteristics of lentigo melanoma include a more indolent course when compared with other types, especially nodular melanoma, which is known for its rapid growth and aggressive nature. Superficial spreading melanoma, while common, also has a tendency to invade more deeply and can metastasize more readily than lentigo melanoma. Desmoplastic melanoma, although it may present as a slow-growing lesion, can still exhibit aggressive behavior, particularly in terms of local recurrence. Overall, the slower progression and the often limited vertical invasion are key factors that contribute to lentigo melanoma being classified as the least aggressive melanoma type.